Category: Jobs

The Zhang lab has recently secured funding to launch a new project with the goal of understanding the epigenetic contributions to tissue stem cell aging. To achieve this goal, we will take a comprehensive approach (data mining, epigenomic profiling, CRISPR-based screen) to identify key epigenetic factors involved in tissue stem cell aging. Then, we will test their role in aging/rejuvenation by targeted epigenomic reprogramming through manipulating these factors.

We are interested in recruiting ambitious and outstanding postdocs to push the technical and conceptual boundaries to reveal the unknowns. Applicants with excellent track record and the following background
are preferred:
• Aging (particularly mouse models of aging)
• Tissue stem cells (NSC, MSC, ISC, HSC, MuSC, etc.)
• Targeted epigenomic editing
• Bioinformatics (with math or computer science BS major)

For more information about the lab and our past work, please visit the lab web site
(https://www.zhanglab.tch.harvard.edu/) and the Google Scholar
(https://scholar.google.com/citations?user=7UjSqHEAAAAJ&hl=en&oi=ao).

Applicants should send their CV and a cover letter explaining why he/she would like to join the team to
Dr. Yi Zhang (yzhang@genetics.med.harvard.edu).

Position Description
Division: Pathology
Work Location: Texas Medical Center, Houston, TX
Title: Post-Doctoral Fellow
Salary Range: According to NIH guide: https://grants.nih.gov/grants/guide/notice-files/NOT-OD-19-036.html plus benefits (https://www.bcm.edu/careers/benefits), commensurate with experience.
The Center for Drug Discovery (https://www.bcm.edu/research/centers/drug-discovery) is a strategic research center established at Baylor College of Medicine in Houston, Texas. We are seeking highly-motivated, organized and enthusiastic Postdoctoral Fellows contributing to the research in the study of the chemical features that facilitate passage across the blood-testis barrier using animal model and LC-MS-based approaches and Imaging Mass Spectrometry (IMS). The center is well equipped with UHPLC-Q Exactive MS, MALDI-IMS and Thermo Quintus (triple quadruple) instruments to conduct LC-MS-based untargeted and targeted metabolomics. Analysis of uptake data for many highly diverse chemical structures will yield predictive rules to inform the development of male contraceptives and other drugs that must accumulate in the male genital tract. Baylor College of Medicine is located in the world-renowned Texas Medical Center and offers a highly interactive environment and a strong infrastructure for research and career development. Job Purpose Performs responsible research work that requires planning, completing, and occasionally supervising research projects in accordance with general plans approved by the supervisor.

Job Duties
• Plan, design and conduct animal experiments, especially on drug metabolism & tissue distribution.
• LC-MS method development and sample preparation, and data analysis.
• Perform cytotoxicity assays
• Document and interpret results of experiments and report to principal investigators.
• Conduct literature searches and summarize information in an appropriate format for a particular study.
• Help to write and prepare manuscripts
• Oversee the maintenance of lab equipment and environment.
• Performs other job related duties as assigned.
Minimum requirements:
• Doctoral degree in pharmacology, toxicology or a related Biomedical Science discipline.

Preferred Qualifications:
• Experience in IMS method development and sample preparation, and data analysis.

• Plan, design and conduct animal experiments, especially on drug metabolism & tissue distribution using IMS methods.

• Prior experience with metabolomics.

Core Competencies

• Builds a logical approach to address problems or opportunities or manage the situation at hand by drawing on own knowledge and experience base and calling on other references and resources as necessary.

• Aware of the industry within which Baylor College of Medicine operates, using knowledge of the organization’s position in the marketplace to enhance competitive advantage.

• Demonstrates knowledge of internal client needs, both current and future; addresses complaints, makes realistic commitments, and effectively communicates needs.

• Willingly cooperates and works collaboratively towards solutions which generally benefit all involved parties; works cooperatively with others to accomplish company objectives; promotes collaboration and partnerships.

• Accepts full responsibility for self and team, confronts problems quickly and builds commitment to organizational success.

• Maintains channels of communication; effectively provides verbal communication and exhibits good listening skills; provides concise, complete, and professional information to others.

Functional Competencies

• Conduct research and development activities to develop new products, technologies and applications.

• Operates and maintains laboratory equipment to support research, operations and technical support.

• Develops new technology solutions based on innovative designs which provide outstanding technology delivery for customers and enable market expansion. • Ensures health and safety standards are world class, achieving and exceeding all legislative requirements. FLSA Status Non-Exempt

Application link:
https://jobs.bcm.edu/job/Houston-Postdoctoral-Associate-Texa/697642200/

Seniority Level

Postdoctoral fellow

Academic

• University and Research
• Biology
• Biotechnology

Employment Type

Full-time

Job Functions

• Research  
• Science

The Gao lab at Rice University (gaolab.rice.edu) is looking for two postdocs who are interested in applying the CRISPR technology to gene therapy and synthetic biology! 

This position is mainly focused on developing the genome editing tools based on CRISPR technologies through rational design and engineering of the effector proteins for further applications in disease treatment, metabolic engineering, and synthetic biology. Experience with molecular biology and cell biology, including mammalian cell and tissue culture, molecular cloning, strain engineering, evolution and screening, recombinant protein expression, purification and engineering, genome editing, nucleic acid in vitro biosynthesis, isolation, and detection are preferred. Please apply the position below jobs.rice.edu/postings/25185 or contact me directly at xue.gao@rice.edu.  

Summary

The section of Gastroenterology & Hepatology is looking to hire a Research Assistant I to manage day to day operations of research projects. The research assistant will be responsible for research work that requires planning, completing, and occasionally supervising limited research projects in accordance with general plans approved by the supervisor.

Job Duties

• Designs and conducts research experiments.
• Collects and analyzes data, presenting weekly to PI
• Assists with Grant Writing.
• Conducts literature searches and summarizes information in an appropriate format for a particular study.
• Documents and interprets results of experiments and reports to principal investigators.
• May develop and modify computer programs.
• Selects and determines appropriate research procedures.
• Oversees the maintenance of lab equipment and environment.

Minimum Qualifications

• Bachelor’s degree in a Basic Science or a related field.
• Two years of relevant experience.

Preferred Qualifications

• Master’s degree in a related field.
• Previously participated in writing medical manuscript.
• Have a minimum of one published article in a journal indexed by Pubmed.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

4692

Seniority Level

Entry level

Industry

• Research 
• Biotechnology 
• Hospital & Health Care

Employment Type

Full-time

Job Functions

• Research 
• Analyst 
• Information Technology